A so, so difficult book to wade through. For you, it might be easy and enjoyable. Still, I had to read it. The times demand it.
I offered only an OK rating of two stars. That’s not to say that this isn’t a well-written book, for the right audience. Walter Isaacson had to have spent an incredible amount of time researching and compiling all the information within it. All those five star ratings and stellar reviews must have come from the right readers who found it great.
This is a science book. Very dense and heavy science. Misled by the many interviews on Walter Isaacson’s book tour, I didn’t realize that I was not among the members of the right audience. I thought this book would spend considerable time (it spent some, just not nearly the amount I expected) on the topics below:
The how and why mRNA and CRISPR were used to create both Pfizer and Moderna’s COVID-19 vaccines–and, most importantly, why reluctant people had nothing to fear from them. [I came away unable to find the words with which I could readily allay those fears of others. I had already happily got my shots, taking on faith the review and approval process–not to mention the lack of reports of any serious ill effects of the Pfizer or Moderna vaccines.]
The ethical quandaries gene editing pose AND the benefits of them for curing diseases. [Yes, looking forward to disease cures but not to enhancements the wealthy will seek for their children].
What then did the book cover?
In excruciating detail, a chronicle of every meeting, conversation, conference and lab experiment, paper submitted/published, patent applied for by hundreds of graduate students, post-docs and more among the biochemists, x-ray crystallographers, structural biologists, engineers, etc., who worked for or under, in competition or collaboration with or supervised Jennifer Doudna enroute to her well deserved Nobel prize that she shared with Emmanuelle Charpentier.